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A NEW APPROACH TO PREVENTING STROKE
DURING OPEN HEART SURGERY


By George L. Hines, MD, FACS
Chief, Division of Vascular Surgery
Department of Thoracic & Cardiovascular Surgery
Winthrop-University Hospital

Stroke occurring during open heart surgery is a devastating complication, not only because of the resulting disability, but also because the patient and family usually do not expect it. About 2-5% of patients undergoing open heart surgery suffer neurologic injury, which occurs even more frequently in older patients.

Many factors can cause the development of a stroke during heart surgery. They include severe atherosclerosis of the aorta, a prolonged period in surgery, and the constriction or narrowing (stenosis) of one or both carotid arteries, which are located in the neck and carry blood to the brain.

Approximately 5-7% of patients undergoing coronary artery bypass surgery have significant co-existing carotid artery disease. In 1994, cardiovascular surgeons in Winthrop-University Hospital's Department of Thoracic and Cardiovascular Surgery conducted a retrospective study to determine whether carotid endarterectomy (the removal of fatty deposits from the vessel's inner lining), performed along with open heart surgery, decreased the risk of having the patient suffer a stroke during the operation. They found that when the vascular procedure was performed along with the cardiac procedure the danger of stroke was significantly lower.

As a result of that study, Winthrop began screening candidates for coronary artery bypass surgery, or coronary artery bypass surgery associated with heart valve replacement, for carotid stenosis prior to surgery. Today, the Hospital's cardiovascular surgeons perform carotid endarterectomies along with coronary artery bypass surgery in patients known to have severe carotid stenosis. Patients found to have stenosis of 80% or greater undergo prophylactic carotid endarterectomy. (Severe carotid stenosis is also considered a leading cause of stroke in patients not undergoing heart surgery. Therefore, prophylactic endarterectomy is regarded as a method of reducing the long-term risk of stroke, overall.)

Over 100 patients have had the combined carotid endarterectomy and open heart surgery procedure. The stroke rate in this group is just below 2%, which is significantly lower than the 5-7% anticipated stroke rate in patients with carotid stenosis of >80% undergoing coronary artery bypass surgery. What's more, no patient has developed a local problem related to the carotid procedure. Winthrop's cardiac and vascular surgeons believe that combining carotid endarterectomy and coronary artery bypass surgery is safe and can significantly reduce the risk of perioperative stroke and long-term neurological events.


REFERENCES
Hines, GL. Scott, WC. Schubach, SC. Kofsky E. Wehbe U. Cabasino, E. Prophylactic Carotid Endarterectomy in Patients with High-Grade Carotid Stenosis Undergoing Coronary Bypass: Does it Decrease the Incidence of Perioperative Stroke? Annals of Vascular Surgery 12:23-27, 1998.

Hines, GL. Scott, WC. Schubach, SL. Tyd, D. Wehbe, U. Hemodynamically Significant Carotid Disease and Prophylactic Carotid Endarterectomy in CABG Patients--Impact on Perioperative Neurologic Events. Vascular Surgery 31:147-151, March/April 1997.



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